Buy Zelboraf 240mg Vemurafenib Online
Brand Name : Zelboraf
Composition : vemurafenib
Manufactured by : ROCHE Pharma Ltd.
Strength : 420 mg
Form : Tablets
Packing : Pack of 120 Tablets
Buy Zelboraf 240mg Tablets of Vemurafenib At onlinecancerpharm.com
What is Zelboraf?
Zelboraf (vemurafenib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Zelboraf is used to treatmelanoma (skin cancer) that has spread to other parts of the body or cannot be removed by surgery.
Zelboraf is also used to treat Erdheim-Chester Disease (a rare blood cancer).
Zelboraf is used only if your cancer has a specific genetic marker (an abnormal “BRAF” gene), for which your doctor will test.
Zelboraf is used to treat melanoma, but this medicine can increase your risk of developing other types of skin cancer. Report any new or worsening skin lesions to your doctor right away.
Many drugs can interact with vemurafenib. Tell your doctor about all your current medicines and any you start or stop using
Before taking this medicine
You should not use Zelboraf if you are allergic to vemurafenib.
To make sure Zelboraf is safe for you, tell your doctor if you have ever had:
- liver or kidney disease;
- heart disease;
- a heart rhythm disorder;
- long QT syndrome (in you or a family member); or
- an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood).
Tell your doctor about all radiation treatments you are scheduled to receive, or have received in the past.
Using Zelboraf may increase your risk of developing other types of skin cancer. Report any new or worsening skin lesions to your doctor right away.
Vemurafenib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine, and for 2 weeks after your last dose. Tell your doctor if you become pregnant.
It is not known whether vemurafenib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Zelboraf and for at least 2 weeks after your last dose.
How should I take Zelboraf?
Take Zelboraf exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take Zelboraf with a full glass of water. You may take this medicine with or without food.
Take the medicine every 12 hours, at the same time each day.
Do not crush, chew, or break a tablet. Swallow the tablet whole.
While using Zelboraf, you may need frequent blood tests to check your liver or kidney function.
To make sure this medication is not causing harmful effects, your skin condition will need to be checked often. Your heart function may also need to be tested with an electrocardiogram (ECG or EKG) on a regular basis. You may also need eye exams. Your cancer treatments may be delayed based on the results of these tests.
Your doctor may want to check your skin for several months after you stop using this medicine. Visit your doctor regularly.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Zelboraf dosing information
Usual Adult Dose for Melanoma – Metastatic:
Maintenance dose: 960 mg orally every 12 hours with or without a meal
Duration of therapy: Treat patients until disease progression or unacceptable toxicity occurs.
-Confirm the presence of BRAF V600E mutation in tumor specimens prior to initiation of treatment.
-A missed dose can be taken up to 4 hours prior to the next dose.
-Do not take an additional dose if vomiting occurs after administration, but continue with the next scheduled dose.
Use: BRAF V600 mutation-positive unresectable or metastatic melanoma
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 4 hours away. Do not take extra medicine to make up the missed dose.
Do not take an extra dose if you vomit shortly after taking Zelboraf. Wait until your next scheduled dose to take the medicine again.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Zelboraf?
Avoid exposure to sunlight or tanning beds. Vemurafenib can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient’s body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Zelboraf side effects
Get emergency medical help if you have signs of an allergic reaction to Zelboraf (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body.Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using Zelboraf.
Stop using this medicine and call your doctor at once if you have:
- skin changes – a new wart or lesion, a skin sore or red bump that bleeds or does not heal, or any change in the size or color of a mole;
- unusual thickening of tissues under the skin on the palms of your hands or the soles of your feet;
- a finger or fingers that feel tight or are bent inward;
- fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
- eye problems – vision changes, eye pain or swelling, severe eye redness, small white or yellow patches on the surface of your eye; or
- liver problems – stomach pain (upper right side), nausea, vomiting, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common Zelboraf side effects may include:
- joint pain;
- feeling tired;
- hair loss;
- mild rash or itching;
- skin growths; or
- sunburn, increased sensitivity to sunlight.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Zelboraf?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can interact with vemurafenib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Follow the following prescription medicine precautions :
|Zelboraf may be harmful for your baby during pregnancy. Take proper medical help in case you are pregnant, may be pregnant or planning to become pregnant in the near future.|
|This medicine is not indicated for use in women. It is not known if Zelboraf is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from Zelboraf a decision should be made to either discontinue nursing, or discontinue the drug taking into account the importance of the drug to the mother.|
|Your health care professional can check blood tests to regularly monitor your liver and kidney function, while you are taking Zelboraf. It is also important to check your levels of blood cells and other substances in the blood.|
|Before taking this medicine, tell your doctor and pharmacist if you are allergic to Zelboraf, any other medications, or any of the ingredients in Zelboraf medicine. This medication is not recommended for use in patients with a known allergy to Zelboraf.|
|If you take Zelboraf, you must stop drinking alcohol. This is one of the ways to prevent this disease from getting worse. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs.|
|If you use other prescription drugs or over the counter products at the same time, the effects of this cancer medicine may change. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that your pharmacist can help you prevent or manage drug interactions.|
|Missing a dose of Zelboraf can upset your treatment plan. If you do miss one of your doses, take it as soon as you remember, unless it’s almost time to take your next dose. In this case, you should just skip the missed dose. Don’t take a double dose to “make up” for the one you missed. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.|
|Do not take Zelboraf the use by (expiry) date printed on the pack. Do not take it if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.|
|During your treatment with Zelboraf, it is very important for your doctor to know about your medical history if you have Kidney problems, hepatitis, liver problems, HIV (human immunodeficiency virus), triglycerides, diabetes or other health problems.|
What are the storage instructions for Zelboraf?
Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.
- Store Zelboraf at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
- Make sure to always keep your medicine in an area of your home that is out of the reach of children and pets.
- Do not store or freeze Zelboraf .
The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.